Rolling the evolutionary dice: Neisseria commensals as proxies for elucidating the underpinnings of antibiotic resistance mechanisms and evolution in human pathogens
K. M. Frost, S. L. Charron-Smith, T. C. Cotsonas, D. C. Dimartino, R. C. Eisenhart, E. T. Everingham, E. C. Holland, K. Imtiaz, C. J. Kornowicz, L. E. Lenhard, L. H. Lynch, N. P. Moore, K. Phadke, M. L. Reed, S. R. Smith, , C. B. Wadsworth
This study uses in vitro evolution of commensal Neisseria species to investigate resistance evolution to azithromycin and penicillin, finding convergent mutations in key resistance mechanisms.
bioRxiv · Sep 26, 2023 · PreprintMicrobiology