Author

S. S. Chng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:E. coli· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. F. Cunningham· 2 shared C. Icke· 2 shared E. Heinz· 2 shared J. A. Bryant· 2 shared Z.-S. Chong· 2 shared A. Colyer· 1 shared A. Delhaye· 1 shared A. Rossiter· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

A. F. Cunningham

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

YhcB coordinates peptidoglycan and LPS biogenesis with phospholipid synthesis during Escherichia coli cell growth.

E. C. A. Goodall, G. L. Isom, J. L. Rooke, C. Icke, K. Pullela, B. Zhang, J. Rae, W. B. Tan, M. Winkle, A. Delhaye, E. Heinz, J.-F. Collet, A. F. Cunningham, M. A. Blaskovich, R. G. Parton, , I. R. Henderson

This study identifies YhcB as a coordinator of peptidoglycan, LPS, and phospholipid synthesis in E. coli, revealing its role in envelope stability and cell size control.

bioRxiv · Apr 16, 2021Microbiology

Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation

J. A. Bryant, F. Morris, T. J. Knowles, R. Maderbocus, E. Heinz, G. Boelter, D. Alodaini, A. Colyer, P. wotherspoon, K. Staunton, M. Jeeves, D. Browning, Y. Sevastsyanovich, T. Wells, A. Rossiter, , i. henderson

This study identifies phospholipid binding as a mechanism for DolP localization, revealing its structure and function in Gram-negative bacteria.

bioRxiv · Aug 10, 2020 · PreprintBiochemistry

Molecular basis for the maintenance of lipid asymmetry in the outer membrane of Escherichia coli

J. Yeow, K. W. Tan, D. A. Holdbrook, Z.-S. Chong, J. K. Marzinek, P. J. Bond, S. S. Chng

The paper defines the molecular architecture of the OmpC-MlaA complex in E. coli and shows how it transports phospholipids across the outer membrane to maintain lipid asymmetry.

bioRxiv · Feb 8, 2018Biochemistry

Outer membrane lipid homeostasis via retrograde phospholipid transport in Escherichia coli

R. Shrivastava, X. Jiang, S. S. Chng

This study identifies the Tol-Pal complex as essential for phospholipid transport and outer membrane lipid homeostasis in Escherichia coli, revealing its role in maintaining lipid asymmetry and OM stability.

bioRxiv · Aug 15, 2017Microbiology

MmpL3 is the flippase for mycolic acids in mycobacteria

Z. Xu, V. A. Meshcheryakov, G. Poce, S. S. Chng

This study identifies MmpL3 as the mycolic acid flippase in mycobacteria and demonstrates BM212 as a direct inhibitor of MmpL3.

bioRxiv · May 3, 2017Biochemistry