Expansion of the prime editing modality with Cas9 from Francisella novicida
Y. Oh, W.-j. Lee, H. Kim, L. W. Gwon, Y.-H. Kim, Y.-H. Park, C. H. Kim, K.-S. Lim, B.-S. Song, J.-W. Huh, S.-U. Kim, B.-H. Jun, C. Jung, S. Lee
This study expands prime editing by linking reverse transcriptase to FnCas9(H969A) nickase, enabling more precise and extended target gene modifications.
bioRxiv · May 25, 2021Bioengineering