Author

D.-S. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

B.-H. Jun· 2 shared H. Kim· 2 shared H. Lee· 2 shared J. K. Hur· 2 shared K.-S. Lim· 2 shared S. H. Lee· 2 shared W. Song· 2 shared W.-j. Lee· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

B.-H. Jun

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Foxp3 Orchestrates Reorganization of Chromatin Architecture to Establish Regulatory T Cell Identity

Z. Liu, D.-S. Lee, Y. Liang, Y. Zheng, J. Dixon

The paper shows Foxp3 is essential for establishing Treg-specific 3D chromatin architecture during differentiation, though not dependent on a specific dimer formation.

bioRxiv · Feb 22, 2023Immunology

Highly specific chimeric DNA-RNA guided genome editing with enhanced CRISPR-Cas12a system

H. Kim, W.-j. Lee, C. H. Kim, Y. Oh, L. W. Gwon, H. Lee, W. Song, J. K. Hur, K.-S. Lim, K. J. Jeong, K.-H. Nam, Y.-S. Won, Y. Lee, Y.-H. Kim, J.-W. Huh, , S. H. Lee

The paper enhances CRISPR-Cas12a system specificity and efficiency using a chimeric DNA-RNA guide, achieving 7.41 and 7.60 times improvements respectively.

bioRxiv · Sep 4, 2021Biochemistry

S100A8/A9 mediate the reprograming of normal mammary epithelial cells induced by dynamic cell-cell interactions with adjacent breast cancer cells.

S. H. Jo, W. H. Heo, M. Quan, B. S. Hong, J. H. Kim, H.-B. Lee, W. Han, Y. Park, D.-S. Lee, N. H. Kwon, M. C. Park, J. Chae, J.-I. Kim, D.-Y. Noh, H.-G. Moon

This study shows that S100A8/A9 mediates the reprogramming of normal mammary epithelial cells by dynamic interactions with breast cancer cells, leading to epithelial-mesenchymal transition and altered cellular behaviors.

bioRxiv · May 2, 2020Cancer Biology

Enhancement of Target Specificity of CRISPR-Cas12a by Using a Chimeric DNA-RNA Guide

H. Kim, W.-j. Lee, S.-H. Kang, J. K. Hur, H. Lee, W. Song, K.-S. Lim, Y.-H. Park, B.-S. Song, Y. B. Jin, B.-H. Jun, D.-S. Lee, S.-U. Kim, S. H. Lee

This study enhances CRISPR-Cas12a specificity by using a chimeric DNA-RNA guide, reducing off-target mutations in genome editing.

bioRxiv · Feb 4, 2020Biochemistry