Author

Satinder K. Samra

Alzheimer’s Research UK

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Paul John WhitingiD· 2 shared Sarah JollyiD· 2 shared Argyro AlatzaiD· 1 shared Bart De StrooperiD· 1 shared Benjamin GaletiD· 1 shared Bernadett KalmáriD· 1 shared Charles ArberiD· 1 shared Dervis A. M. SalihiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Paul John WhitingORCID

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2 papers

Recent·Most cited

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis

Oliver Jonathan Ziff, Gustavo Morrone Parfitt, Sarah Jolly, Jackie M. Casey, Lucy Granat, Satinder K. Samra, Núria Setó‐Salvia, Argyro Alatza, Leela Phadke, Benjamin Galet, Philippe Ravassard, Marie‐Claude Potier, John Hardy, Dervis A. M. Salih, Paul John Whiting, , Charles Arber

This study shows that PSEN1 mutations disrupt regulated intramembrane proteolysis in astrocytes, leading to enhanced inflammatory responses and contributing to familial Alzheimer's disease progression.

Molecular Neurodegeneration · Jun 20, 2025Peer-reviewedNeuroscience

Microglial expression of the Wnt signalling modulator DKK2 differs between human Alzheimer's disease brains and mouse neurodegeneration models

Nozie D. Aghaizu, Sarah Jolly, Satinder K. Samra, Bernadett Kalmár, Katleen Craessaerts, Linda Greensmith, Patricia C. Salinas, Bart De Strooper, Paul John Whiting

This study compares microglial DKK2 expression in mouse AD models and human AD brains, finding upregulation in mice but not in humans.

bioRxiv · May 5, 2022 · PreprintNeuroscience