Argyro Alatza

This paper shows metformin protects neurons by stabilizing rngo/DDI2, enhancing proteostasis and reducing toxicity in multiple neurodegenerative models.

The paper identifies oxidized MIF as a drug target that links HSV-1 infection and external stressors to tau pathology in Alzheimer's disease.

This study shows that PSEN1 mutations disrupt regulated intramembrane proteolysis in astrocytes, leading to enhanced inflammatory responses and contributing to familial Alzheimer's disease progression.

This paper introduces a new mouse model, NLFTaum/h, that shows ageing and amyloid-β can initiate tau pathology without MAPT mutations, revealing interactions between age, Aβ, and human tau.