Author

Scarlett Varley

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Brett A. KaufmaniD· 1 shared Byron W. Chuan· 1 shared Claudette M. St. CroixiD· 1 shared Corrine R. KlimentiD· 1 shared Delphine BeaulieuiD· 1 shared E L Huang· 1 shared Jian Shi· 1 shared John SembratiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Brett A. KaufmanORCID

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1 paper

Recent·Most cited

Alveolar Epithelial Cell Loss of the Mitochondrial Regulator TFAM Drives Progressive Lung Fibrosis

Qianjiang Hu, Ugochi Onwuka, Nayra Cárdenes, M Packwood, E L Huang, Jian Shi, M. Camila Melo-Narváez, Puja Dutta, Zihe Zhou, Delphine Beaulieu, Byron W. Chuan, Pavan Suresh, Kevin Redding, Laura-Marie Twardowski, Scarlett Varley, , Mélanie Königshoff

This study shows that loss of TFAM in alveolar type 2 cells leads to mitochondrial dysfunction and fibrosis by promoting senescence and a profibrotic secretory program.

bioRxiv · Jul 18, 2026 · PreprintPathology