Author

Zihe Zhou

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Oliver EickelbergiD· 2 shared Barsha Dash· 1 shared Bingpeng YaoiD· 1 shared Brett A. KaufmaniD· 1 shared Byron W. Chuan· 1 shared Claudette M. St. CroixiD· 1 shared Corrine R. KlimentiD· 1 shared Darrell N. KottoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPathology

Oliver EickelbergORCID

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Author profile →

2 papers

Recent·Most cited

Alveolar Epithelial Cell Loss of the Mitochondrial Regulator TFAM Drives Progressive Lung Fibrosis

Qianjiang Hu, Ugochi Onwuka, Nayra Cárdenes, M Packwood, E L Huang, Jian Shi, M. Camila Melo-Narváez, Puja Dutta, Zihe Zhou, Delphine Beaulieu, Byron W. Chuan, Pavan Suresh, Kevin Redding, Laura-Marie Twardowski, Scarlett Varley, , Mélanie Königshoff

This study shows that loss of TFAM in alveolar type 2 cells leads to mitochondrial dysfunction and fibrosis by promoting senescence and a profibrotic secretory program.

bioRxiv · Jul 18, 2026 · PreprintPathology

Mesothelial Plasticity Specifies a Pleural Immune Circuit that Orchestrates Lung Regeneration

Le Xu, Kevin H. Chen, Barsha Dash, Bingpeng Yao, Rongbo Li, Xingan Wang, Zihe Zhou, Vincent Yu, Rebecca J. Salamon, Pushpinder Bawa, Minzhe Guo, Zea Borok, Darrell N. Kotton, Oliver Eickelberg, Marta Bueno, Xin Sun

The paper identifies mesothelial cell plasticity as a key determinant of regenerative versus degenerative lung repair by comparing pneumonectomy and chronic lung allograft dysfunction models.

bioRxiv · Jun 29, 2026 · PreprintDevelopmental Biology