Author

Seunghee Lee

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Adam AndruskaiD· 1 shared Aiqing Cao· 1 shared Brian S. GarrisoniD· 1 shared Cerianne Huang· 1 shared Dan YiiD· 1 shared Dongeon KimiD· 1 shared Evan Bao· 1 shared Han Deng· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Adam AndruskaORCID

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2 papers

Recent·Most cited

Tunable Universal OR-gated CAR T cells for AML

Md Nure Alom Siddiqui, Jingyao Chen, Juanjuan Huang, Madeline K. Loffredo, Seunghee Lee, Han Deng, Yongshuai Li, Nelia Leemans, Tim Lu, Brian S. Garrison, Marcela Guzman Ayala, Nicholas W. Frankel, Wilson W. Wong

This study develops a tunable OR-gated CAR system for AML treatment that effectively targets multiple antigens with reduced engineering complexity and minimized off-target toxicity.

iScience · Aug 1, 2026Peer-reviewedSynthetic Biology

EBF1 controls an embryonic artery-forming niche that reactivates in pulmonary arterial hypertension

Wen Tian, Ting-Hsuan Wu, Shenbiao Gu, Seunghee Lee, Hanqiu Zhao, Adam Andruska, Kyle K. Song, Jason Chang, Cerianne Huang, Ryan Vinh, Dongeon Kim, Yu Zhu, Evan Bao, Stuti Agarwal, Dan Yi, , Mark Robert Nicolls

This study identifies EBF1 as a regulator of embryonic artery formation and shows its reactivation in pulmonary arterial hypertension drives pathological vascular remodeling.

bioRxiv · May 2, 2025 · PreprintDevelopmental Biology