Sexually dimorphic role of estrogen receptor α in preserving right ventricular endothelial integrity
Jiajun Li, Vijaya Karoor, Andrea L. Frump, Hanqiu Zhao, Shu Ying Liang, Chen-Shan Chen Woodcock, Irina Petrache, Zhiyu Dai, Tim Lahm
This study shows estrogen receptor α protects female RV endothelial cells from apoptosis and supports angiogenesis in pulmonary hypertension, revealing a sex-specific role in RV function.
Arteriosclerosis Thrombosis and Vascular Biology · Sep 10, 2026Peer-reviewedCell Biology