Author

Shannah Serres

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Brennon L. O’CallaghaniD· 4 shared Harry T. OrriD· 4 shared Lisa A. DuvickiD· 4 shared Orion RainwateriD· 4 shared Alyssa SolesiD· 3 shared Marija CvetanovićiD· 3 shared Praseuth YangiD· 3 shared Hillary P. HandleriD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Brennon L. O’CallaghanORCID

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Author profile →

4 papers

Recent·Most cited

A neural basis for mutant ATAXIN-1 induced respiratory dysfunction in mouse models of Spinocerebellar ataxia type 1

Alyssa Soles, Jessica M. L. Grittner, Kaia Douglas, Praseuth Yang, Lisa A. Duvick, Brennon L. O’Callaghan, Ryan Barnett, Christine Chau, Ronin Joshua S. Cosiquien, Orion Rainwater, Shannah Serres, Brendan J. Dougherty, Harry T. Orr, Marija Cvetanović

This study identifies mutant ATAXIN-1's role in respiratory dysfunction in SCA1 mice by analyzing neural and skeletal muscle lineages.

Neurobiology of Disease · Mar 17, 2026Peer-reviewedNeuroscience

Striatal pathology in Spinocerebellar Ataxia Type 1 mice: A comparative study with Huntingtons disease

Pragya Goel, Praseuth Yang, Lisa A. Duvick, Orion Rainwater, Shannah Serres, Brennon L. O’Callaghan, Rocío Gómez‐Pastor, Mustafa Hussain Mehkary, Terence Gall-Duncan, Peter Langfelder, X. William Yang, Christopher E. Pearson, Patrick E. Rothwell, Harry T. Orr

This study compares striatal pathology in SCA1 and HD mice, finding shared and distinct molecular and functional deficits in Medium Spiny Neurons.

bioRxiv · Dec 14, 2025 · PreprintNeuroscience

Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse

Lisa A. Duvick, William M. Southern, Kellie A. Benzow, Zoe N. Burch, Hillary P. Handler, Jason S. Mitchell, Hannah Kuivinen, Udaya Keerthy Gadiparthi, Praseuth Yang, Alyssa Soles, Carrie A. Sheeler, Orion Rainwater, Shannah Serres, Erin B. Lind, Tessa Nichols‐Meade, , Harry T. Orr

This study identifies brain regions and cell types contributing to SCA1 disease using conditional knockout mice, showing that targeting multiple areas and muscle is necessary for effective therapy.

bioRxiv · Feb 8, 2023 · PreprintNeuroscience

Disrupting ATXN1 Nuclear Localization in a Knock-in SCA1 Mouse Model Improves a Spectrum of SCA1-Like Phenotypes and their Brain Region Associated Transcriptomic Profiles

Hillary P. Handler, Lisa A. Duvick, Jason S. Mitchell, Marija Cvetanović, Molly Reighard, Alyssa Soles, Orion Rainwater, Shannah Serres, Tessa Nichols‐Meade, Stephanie L. Coffin, Yun You, Brian L. Ruis, Brennon L. O’Callaghan, Christine M. Henzler, Huda Yahya Zoghbi, Harry T. Orr

This study shows disrupting ATXN1 nuclear localization in a SCA1 mouse model reduces disease-like phenotypes and alters region-specific transcriptomic profiles.

bioRxiv · Dec 16, 2021 · PreprintNeuroscience