Author

Silvia Schirge

Helmholtz Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Heiko LickertiD· 3 shared Christopher B. MulhollandiD· 1 shared Ciro SalinnoiD· 1 shared Derk ten BergeiD· 1 shared Emiel van Genderen· 1 shared Eunike Sawitning Ayu SetyonoiD· 1 shared Flora C. Y. LeeiD· 1 shared Heinrich LeonhardtiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Heiko LickertORCID

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Author profile →

3 papers

Recent·Most cited

Endocrine-enriched stem cell-derived islets improve long-term safety in vivo

Eunike Sawitning Ayu Setyono, Nicole Katarina Rogers, Katharina Scheibner, Silvia Schirge, Hélène Reich, Michael Sterr, Timucin Öztürk, Sören Franzenburg, Väinö Lithovius, Heiko Lickert

This study improves the safety of stem cell-derived islets by enriching endocrine cells and reducing off-target cell types, enhancing long-term in vivo outcomes.

bioRxiv · Aug 22, 2025 · PreprintBioengineering

Generation of a novel Nkx6-1 Venus fusion reporter mouse line

Ingo Burtscher, Marta Tarquis-Medina, Ciro Salinno, Silvia Schirge, Julia Beckenbauer, Mostafa Bakhti, Heiko Lickert

This paper generates a Nkx6-1 Venus fusion reporter mouse line to track and isolate Nkx6-1-expressing cells, including pancreatic β-cells, during development and in adult tissues.

International Journal of Molecular Sciences · Mar 26, 2021Peer-reviewedDevelopmental Biology

Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation

Miha Modic, Igor Ruiz de los Mozos, Sebastian Steinhauser, Emiel van Genderen, Silvia Schirge, Valter Bergant, Joël Ryan, Christopher B. Mulholland, Rupert Faraway, Flora C. Y. Lee, Tajda Klobučar, Juliane Merl‐Pham, Stephanie M Hauck, Micha Drukker, Sebastian Bultmann, , Jernej Ule

The paper identifies LIN28A as a key factor in mRNA decay during epiblast morphogenesis, linking cell identity changes to embryonic growth through nucleo-cytoplasmic translocation.

bioRxiv · Mar 15, 2021 · PreprintDevelopmental Biology