Author

Spoorthi Sadasivuni

The University of Texas at Dallas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Asta Arendt-TranholmiD· 2 shared Jayden A. O'BrieniD· 2 shared Joseph B. LesnakiD· 2 shared Theodore John PriceiD· 2 shared Amol M. PatwardhaniD· 1 shared Armen N. AkopianiD· 1 shared Eroboghene E. UboguiD· 1 shared Hemanth MydugolamiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Asta Arendt-TranholmORCID

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2 papers

Recent·Most cited

T-cell distribution in the dorsal root ganglion across species, sex, and age

Jayden A. O'Brien, Nishka Kuttanna, Khadijah Mazhar, Marisol Mancilla Moreno, Asta Arendt-Tranholm, Joseph B. Lesnak, Michael A Wilde, Spoorthi Sadasivuni, Pooja J. Patel, Rainer Viktor Haberberger, Armen N. Akopian, Stephanie Hennen, Verena Arndt, Jane M Brandon, Katherin A. Gabriel, , Theodore John Price

The paper investigates T-cell distribution in the dorsal root ganglion across species, sex, and age, finding similar levels in humans, non-human primates, and pigs, but fewer in rats and absent in mice, with sex and age differences in humans.

bioRxiv · May 5, 2026 · PreprintNeuroscience

Nerve-targeting and pain-promoting transcriptomic signatures in early Guillain-Barre syndrome

Jayden A. O'Brien, Joseph B. Lesnak, Ishwarya Sankaranarayanan, Asta Arendt-Tranholm, Nikhil Nageshwar Inturi, Spoorthi Sadasivuni, Hemanth Mydugolam, Katelyn E. Sadler, Theodore John Price, Eroboghene E. Ubogu

This study identifies transcriptomic signatures in GBS patients that reveal leukocyte interactions with peripheral nerves and pain pathways, suggesting therapeutic targets for neuropathic pain.

bioRxiv · Sep 24, 2025 · PreprintNeuroscience