Author

Srilakshmi Goberdhan

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aimee J. AylwardiD· 1 shared Allison KnuppiD· 1 shared Cheryl PaniD· 1 shared Courtney R. BenoitiD· 1 shared David Alan BennettiD· 1 shared Duc Minh DuongiD· 1 shared Hans‐Ulrich KleiniD· 1 shared Hyo LeeiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aimee J. AylwardORCID

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1 paper

Recent·Most cited

Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1

Hyo Lee, Aimee J. Aylward, Richard V. Pearse, Yi‐Chen Hsieh, Zachary M. Augur, Courtney R. Benoit, Vicky Chou, Allison Knupp, Cheryl Pan, Srilakshmi Goberdhan, Duc Minh Duong, Nicholas T. Seyfried, David Alan Bennett, Hans‐Ulrich Klein, Philip L. De Jager, , Tracy L. Young‐Pearse

This study shows that SORL1 loss reduces APOE levels specifically in neurons and astrocytes, linking SORL1 and APOE to Alzheimer's disease risk through distinct pathways.

bioRxiv · Feb 25, 2023 · PreprintNeuroscience