Author

Steven N Dahmen

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:Xenopus· 3 Assay:DNA methylation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

James M. DewariD· 3 shared David CorteziD· 2 shared Matthew T. CranfordiD· 2 shared Darren R. HeintzmaniD· 1 shared David T Long· 1 shared Gábor M. HaramiiD· 1 shared Keir Cajal NeumaniD· 1 shared Lillian V. Campos· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

James M. DewarORCID

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Author profile →

3 papers

Recent·Most cited

Topoisomerase IIIα resolves inter- and intra-molecular intertwines during DNA replication

Sabrina X. Van Ravenstein, Lillian V. Campos, Gábor M. Harami, Darren R. Heintzman, Steven N Dahmen, William G. Dunphy, Keir Cajal Neuman, James M. Dewar

This study shows that TOP3 resolves both inter- and intra-molecular DNA intertwines during replication, promoting fork progression and daughter strand unlinking, especially when TOP2 is compromised.

bioRxiv · Jul 1, 2026 · PreprintBiochemistry

Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms

Matthew T. Cranford, Steven N Dahmen, David Cortez, James M. Dewar

The paper investigates how abasic sites on leading and lagging strands affect replisome progression and bypass mechanisms in Xenopus egg extracts, showing distinct stalling effects but similar reliance on translesion synthesis.

Nucleic Acids Research · Sep 12, 2025Peer-reviewedBiochemistry

Resolution of collapsed forks is separate from completion of DNA synthesis

Sara C. Conwell, Steven N Dahmen, Matthew T. Cranford, Ruthie Mulvaney, David T Long, David Cortez, James M. Dewar

The paper shows that replication fork collapse at SSBs leads to seDSBs resolved by homologous recombination, but DNA synthesis downstream is inefficient, while deDSBs allow efficient synthesis without recombination.

bioRxiv · Mar 3, 2025 · PreprintBiochemistry