H4K16ac activates transcription of transposable elements and contribute to their cis regulatory function
Debosree Pal, Manthan Patel, Fanny Boulet, Sundarraj Jayakumar, Olivia A. Grant, Miguel Ramos Branco, Srinjan Basu, Silvia D. M. Santos, Nicolae Radu Zabet, Paola Scaffidi, Madapura M. Pradeepa
The paper shows H4K16ac activates LINE1 and LTR transcription, contributing to cis-regulatory function by maintaining active chromatin at TEs.
Nature Structural & Molecular Biology · Jun 12, 2023Peer-reviewedMolecular Biology