Author

T. A. Daugird

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

W. R. Legant· 4 shared Y. Shi· 3 shared K. L. Holland· 2 shared L. D. Lavis· 2 shared A. Giovannucci· 1 shared A. N. Tkachuk· 1 shared A. Sau· 1 shared B. D. Strahl· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersBiophysics

W. R. Legant

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4 papers

Recent·Most cited

A posterior approach to correct for focal plane offsets in lattice light sheet structured illumination microscopy

Y. Shi, T. A. Daugird, W. R. Legant

This paper introduces a method to detect and correct axial offset between excitation and detection focal planes in latticeSIM to reduce image artifacts.

bioRxiv · Apr 26, 2024Biophysics

A series of spontaneously blinking dyes for super-resolution microscopy

K. L. Holland, S. E. Plutkis, T. A. Daugird, A. Sau, J. B. Grimm, B. P. English, Q. Zheng, S. Dave, F. Rahman, L. Xie, P. Dong, A. N. Tkachuk, T. A. Brown, R. H. Singer, Z. J. Liu, , L. D. Lavis

This paper introduces a series of spontaneously blinking dyes with adjustable duty cycles for improved single-molecule localization microscopy in cells and dense structures.

bioRxiv · Feb 23, 2024Cell Biology

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment

T. A. Daugird, Y. Shi, K. L. Holland, H. Rostamian, Z. Liu, L. D. Lavis, J. Rodriguez, B. D. Strahl, W. R. Legant

The paper uses correlative single molecule lattice light sheet imaging to study nucleosome dynamics and chromatin environment interactions in live cells, revealing differential diffusion and packing with increasing chromatin density.

bioRxiv · Nov 9, 2023Biophysics

Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events

Y. Shi, J. S. Tabet, D. E. Milkie, T. A. Daugird, C. Q. Yang, A. Giovannucci, W. R. Legant

The paper introduces smartLLSM, an AI-controlled microscope that switches imaging modes to capture rare cellular events, revealing mitotic dynamics and drug effects with high spatiotemporal resolution.

bioRxiv · Mar 7, 2023Biophysics