Author

D. E. Milkie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:imaging· 3 Research Focus:cell type annotation· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

E. Betzig· 2 shared A. Chen· 1 shared A. Giovannucci· 1 shared A. Kililea· 1 shared A. Shirinifard· 1 shared C. Q. Yang· 1 shared C. Rodriguez· 1 shared C. S. Xu· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

E. Betzig

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization, Comparison, and Optimization of Lattice Light Sheets

X. Ruan, G. Liu, D. E. Milkie, F. Gorlitz, M. Mueller, W. Hercule, A. Kililea, E. Betzig, S. Upadhyayula

This paper compares and optimizes lattice light sheets to improve resolution and reduce photobleaching in light sheet microscopy.

Science Advances · Mar 31, 2023Peer-reviewedCell Biology

Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events

Y. Shi, J. S. Tabet, D. E. Milkie, T. A. Daugird, C. Q. Yang, A. Giovannucci, W. R. Legant

The paper introduces smartLLSM, an AI-controlled microscope that switches imaging modes to capture rare cellular events, revealing mitotic dynamics and drug effects with high spatiotemporal resolution.

bioRxiv · Mar 7, 2023Biophysics

An adaptive optics module for deep tissue multiphoton imaging in vivo

C. Rodriguez, A. Chen, J. A. Rivera, M. A. Mohr, Y. Liang, W. Sun, D. E. Milkie, T. G. Bifano, X. Chen, N. Ji

This paper develops an adaptive optics module for multiphoton imaging in vivo, enabling high-resolution visualization of neural structures and calcium responses in deep brain and spinal cord regions of mice.

bioRxiv · Nov 25, 2020Bioengineering

Correlative three-dimensional super-resolution and block face electron microscopy of whole vitreously frozen cells

D. P. Hoffman, G. Shtengel, C. S. Xu, K. R. Campbell, M. Freeman, L. Wang, D. E. Milkie, H. A. Pasolli, N. Iyer, J. A. Bogovic, D. R. Stabley, A. Shirinifard, S. Pang, D. Peale, K. Schaefer, , H. F. Hess

This study develops a platform for 3D correlative cryogenic super-resolution and block-face EM of whole vitreously frozen cells, revealing new protein-ultrastructure relationships.

bioRxiv · Sep 18, 2019Cell Biology