Author

T. H. Mann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

B. Mcdonald· 2 shared D. Chen· 2 shared E. Casillas· 2 shared H. K. Chung· 2 shared L. Shapiro· 2 shared Q. Yang· 2 shared S. K. Varanasi· 2 shared S. M. Kaech· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

B. Mcdonald

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Atlas-Guided Discovery of Transcription Factors for T Cell Programming

H. K. Chung, C. Liu, A. Battu, A. N. Jambor, B. M. Pratt, F. Xie, B. P. Riesenberg, E. Casillas, M. Sun, E. Landoni, Y. Li, Q. Ye, D. Joo, J. Green, Z. Syed, , S. M. Kaech

The paper identifies transcription factors driving distinct CD8+ T cell states and shows their impact on tumor control and immunotherapy.

bioRxiv · Jan 3, 2023Immunology

A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma

D. Chen, S. K. Varanasi, T. Hara, K. Traina, B. McDonald, Y. Farsakoglu, J. Clanton, S. Xu, T. H. Mann, V. Du, H. K. Chung, Z. Xu, V. Tripple, E. Casillas, S. Ma, , S. M. Kaech

This study identifies a microglia-CD4+ T cell interaction that enhances anti-glioblastoma immunity through IFN-gamma-mediated tumor surveillance and phagocytosis.

bioRxiv · Aug 12, 2022 · PreprintImmunology

Integration of cell cycle signals by multi-PAS domain kinases

T. H. Mann, L. Shapiro

The paper shows how multi-PAS domain kinases integrate subcellular signals to control kinase-phosphatase activity in Caulobacter crescentus.

bioRxiv · May 16, 2018Biochemistry

Phospho-signal flow from a pole-localized microdomain spatially patterns transcription factor activity

K. Lasker, A. von Diezmann, D. G. Ahrens, T. H. Mann, W. E. Moerner, L. Shapiro

The paper studies how a microdomain at the cell pole of Caulobacter crescentus spatially patterns transcription factor activity through phospho-signaling.

bioRxiv · Feb 21, 2018Cell Biology