Author

M. Karnat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J.-F. Rupprecht· 4 shared C. Jebane· 2 shared S.-Z. Lin· 2 shared A. Arora· 1 shared A. Gros· 1 shared A. Lecchi· 1 shared A. Viallat· 1 shared A.-A. Varlet· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiophysics

J.-F. Rupprecht

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Author profile →

4 papers

Recent·Most cited

DARE: Division Axis and Region Estimation from 2D and 3D Time-Lapse Images

R. Karpinski, A. Gros, M. Karnat, Q. Saaheelur Rahaman, J. Vanaret, M. Saadaoui, S. L. Tlili, J.-F. Rupprecht

The paper introduces a two-stage framework for detecting cell divisions in 2D and 3D time-lapse images using segmentation and regression models, achieving high accuracy with efficient architectures.

bioRxiv · Feb 5, 2024 · PreprintBiophysics

E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes.

C. Fu, F. Dilasser, S.-Z. Lin, M. Karnat, A. Arora, H. Rajendiran, H. T. Ong, N. M. Hoon, S. W. Phow, T. Hirashima, M. Sheezt, J.-F. Rupprecht, S. Tlili, V. Viasnoff

bioRxiv · Dec 4, 2023 · PreprintCell Biology

Enhanced cell viscosity: a new phenotype associated withlamin A/C alterations

C. Jebane, A.-A. Varlet, M. Karnat, L. M. Hernandez-Cedillo, A. Lecchi, F. Bedu, C. Desgrouas, C. Vigouroux, M.-C. Vantyghem, A. Viallat, J.-F. Rupprecht, E. Helfer, C. Badens

This study quantifies whole cell mechanical changes caused by lamin A/C alterations using microfluidic experiments, revealing increased long-time viscosity as a potential diagnostic marker.

bioRxiv · Jul 18, 2022Biophysics

Mechanical stress driven by rigidity sensing governs epithelial stability

S. Sonam, L. Balasubramaniam, S.-Z. Lin, I. Yow, I. P. Jauma, C. Jebane, M. Karnat, Y. Toyama, P. Marcq, J. Prost, R.-M. Mege, J.-F. Rupprecht, B. Ladoux

The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.

bioRxiv · Mar 10, 2022Biophysics