A. Miyawaki

Single MAPT knock-in mouse models of frontotemporal dementia for sharing with the neurodegenerative research community

The paper describes the development of triple MAPT mutation knock-in mice that exhibit early tau pathology and behavioral abnormalities, useful for studying frontotemporal dementia and related tauopathies.

Comparison of monomeric variants of StayGold

This study compares three monomeric variants of StayGold to evaluate their photostability, brightness, and dispersibility, highlighting tradeoffs in fluorescent protein technology.

StayGold Photostability under Different Illumination Modes

This study compares the photostability of StayGold with three other FPs under different illumination modes in microscopy, finding that StayGold maintains superior photostability in multi-beam LSCM but shows variable performance in single-beam LSCM.

Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging

This paper develops two mouse strains with Cre-dependent luciferases for in vivo imaging, showing distinct emission spectra and improved brightness for specific tissues.

Two new coral fluorescent proteins of distinct colorsfor sharp visualization of cell-cycle progression

The paper describes two new coral fluorescent proteins, h2-3 and 1-41, and their application in creating a new Fucci variant for improved cell-cycle visualization.

Spatial frequency-based correction of the spherical aberration in living brain imaging

The paper introduces a new spatial frequency-based algorithm, Peak-F, for spherical aberration correction in living brain imaging, showing it outperforms the contrast-based Peak-C method in low signal-to-noise ratio conditions.

Integrative analysis of scRNAs-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

The paper identifies transit-amplifying thymic epithelial cells expressing Aire and CD80 through integrative scRNA-seq and scATAC-seq analysis.

Metastatic Single Tumor Cells Evade NK Cell-mediated Killing by Thrombin-mediated Loss of the Activating Ligand CD155/PVR/Necl-5

The paper shows metastatic tumor cells evade NK cell killing by losing CD155/PVR/Necl-5 via thrombin, allowing survival in lung capillaries.

Moments reconstruction and local dynamic range compression of high order Superresolution optical fluctuation imaging

This paper compares high order moments and cumulants SOFI reconstructions, showing that moments are free of cusp artifacts and enable improved resolution through deconvolution.