Author

T. Hollin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

K. G. Le Roch· 4 shared S. Abel· 4 shared J. Prudhomme· 3 shared A. Saraf· 2 shared C. Banks· 2 shared G. Batugedara· 2 shared L. Florens· 2 shared T. Lenz· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

K. G. Le Roch

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Potent Kalihinol Analogue Disrupts Apicoplast Function and Vesicular Trafficking in P. falciparum Malaria.

Z. M. Chahine, S. Abel, T. Hollin, J. H. Chung, G. L. Barnes, M. E. Daub, I. Renard, J. Y. Choi, P. Vydyam, A. Chattopadhyay Pal, M. Argomaniz, C. Banks, J. kirkwood, A. Saraf, I. Camino Diaz, , K. G. Le Roch

This paper identifies MED6-189, a potent antimalarial compound that disrupts apicoplast function and vesicular trafficking in P. falciparum, showing efficacy against drug-resistant strains and demonstrating a unique mechanism of action.

bioRxiv · Nov 21, 2023 · PreprintMicrobiology

PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

Z. M. Chahine, M. Gupta, T. Lenz, T. Hollin, S. Abel, C. Banks, A. Saraf, J. Prudhomme, S. Bhanvadia, L. Florens, K. G. Le Roch

This study shows PfMORC regulates chromatin structure and gene repression in Plasmodium falciparum, essential for parasite survival and a potential target for antimalarial drugs.

bioRxiv · Sep 11, 2023Microbiology

Characterization of GEXP15 as a potential regulator of Protein Phosphatase 1 and partner of ribosomal complex in Plasmodium falciparum.

H. Mansour, A. Cabezas-Cruz, V. Peucelle, A. Farce, S. Salome-Desnoulez, I. Metatla, I. C. Guerrera, T. Hollin, J. Khalife

This study identifies GEXP15 as a regulator of PP1 and ribosomal complex in Plasmodium falciparum, enhancing PP1 phosphatase activity and suggesting it as a drug target.

bioRxiv · Jul 4, 2023 · PreprintMicrobiology

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite.

G. Batugedara, X. M. Lu, S. Abel, Z. Chahine, B. Hristov, D. Williams, T. Hollin, T. Wang, A. Cort, T. Lenz, T. Thompson, J. Prudhomme, A. K. Tripathi, G. Xu, J. Cudini, , K. G. Le Roch

This study identifies and characterizes long non-coding RNAs (lncRNAs) in Plasmodium falciparum, revealing their role in gene regulation, pathogenicity, and sexual differentiation.

bioRxiv · Oct 12, 2022 · PreprintMicrobiology

Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission

R. Pandey, S. Abel, M. Boucher, R. J. Wall, M. Zeeshan, E. Rea, A. Freville, X. M. Lu, D. Brady, E. Daniel, R. R. Stanway, S. Wheatley, G. Batugedara, T. Hollin, A. R. Bottrill, , R. Tewari

bioRxiv · Dec 22, 2019Cell Biology