J. Y. Choi

Transposition, duplication, and divergence of the telomerase RNA underlies the Mimulus telomere evolution

The paper identifies transposition, duplication, and divergence of the telomerase RNA as the mechanism driving telomere sequence evolution in Mimulus species.

A Potent Kalihinol Analogue Disrupts Apicoplast Function and Vesicular Trafficking in P. falciparum Malaria.

This paper identifies MED6-189, a potent antimalarial compound that disrupts apicoplast function and vesicular trafficking in P. falciparum, showing efficacy against drug-resistant strains and demonstrating a unique mechanism of action.

Nascent transcription and the associated cis-regulatory landscape in rice

This study identifies transcribed intergenic regions in rice that function as regulatory elements, associated with gene expression and chromatin interactions.

Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago

This study investigates how ancient genetic variations drive adaptive radiation in Hawaiian Metrosideros, showing balancing selection on pre-existing haplotypes facilitates diversification despite limited genetic diversity.

Nasal commensal, Staphylococcus epidermidis shapes the mucosal environment to prevent influenza virus invasion through Serpine1 induction

This paper shows that Staphylococcus epidermidis in the nasal mucosa induces Serpine1, which blocks influenza virus invasion by inhibiting protease activity and IFN-λ signaling.

A Small interfering RNA lead targeting RNA-dependent RNA-polymerase effectively inhibit the SARS-CoV-2 infection in Golden Syrian hamster and Rhesus macaque

The paper screens siRNA molecules to target SARS-CoV-2 and shows that an RdRp-targeting siRNA reduces infection in hamsters and macaques.

Telomere lengths in plants are correlated with flowering time variation

The paper finds a negative correlation between telomere length and flowering time in Arabidopsis thaliana, rice, and maize, suggesting a link between telomere dynamics and plant life history strategies.

Genomic history and ecology of the geographic spread of rice

The paper reconstructs the ancient dispersal of rice in Asia and identifies extrinsic factors affecting its genomic diversity.

Nanopore-based genome assembly and the evolutionary genomics of basmati rice

The paper assembles high-quality genomes of two basmati rice varieties using nanopore sequencing and identifies structural variations, gene flow, and genetic groupings in circum-basmati rice.

Divergent selection and primary gene flow shape incipient speciation of a riparian tree on Hawaii Island

This study investigates the role of divergent selection and gene flow in the incipient speciation of a riparian tree in Hawaii, finding genomic islands of divergence linked to regulatory genes and positive selection.

Impact of Chronic Total Occlusion Lesion Length onSix-month Angiographic and 2-year Clinical Outcomes

This study compares 6-month angiographic and 2-year clinical outcomes between long and short chronic total occlusion (CTO) lesions after successful DES PCI, finding higher repeat PCI rates in long CTO lesions.

The complex geography of domestication of the African rice Oryza glaberrima

This paper investigates the domestication history of African rice, finding no single origin and suggesting a multi-regional process with admixture and multiple contributing regions.

Multiple origin but single domestication led to domesticated Asian rice

This study reanalyzes rice domestication data to show multiple origins but single domestication event with allele introgression.