T. Kanazawa

Genetic and phosphoproteomic basis of LysM-mediated immune signaling in Marchantia polymorpha highlights conserved elements and new aspect of pattern-triggered immunity in land plants

This study identifies LysM receptor components and phosphoproteomic regulators of PTI in M. polymorpha, revealing conserved and novel elements of plant immune signaling.

The Arabidopsis V-ATPase is localized to the TGN/EE via a seed plant specific motif and acts in a partially redundant manner with the tonoplast enzyme

This study identifies a seed plant-specific motif in Arabidopsis VHA-a1 that targets the V-ATPase to the TGN/EE and shows partial functional redundancy with tonoplast-localized VHA-a2 and VHA-a3.

Membrane-proximal external region is a superior target for mediating effector activity of HIV-1 specific chimeric antigen receptor modified T cells.

This paper develops a multicolor flow cytometry assay to compare anti-HIV-1 activity of different CAR constructs and identifies that CARs targeting the membrane-proximal external region show higher cytotoxicity than CD4{zeta} CAR.

Switching secretory pathway direction for organelle acquisition in plants

The paper identifies a mechanism in liverworts for acquiring oil bodies through switching secretory pathway direction during cellular phase transitions.

Oil body formation in Marchantia polymorpha is controlled by MpC1HDZ and serves as a defense against arthropod herbivores

This study identifies MpC1HDZ as a transcription factor controlling oil body formation in liverworts, which functions as a defense against herbivores rather than abiotic stress.