H. Nakagami

The leucine-rich repeat receptor kinase QSK1 is a novel regulator of PRR-RBOHD complex and is employed by the bacterial effector HopF2Pto to modulate plant immunity

The paper identifies QSK1 as a novel negative regulator of PRR-RBOHD complex and shows it is targeted by the bacterial effector HopF2Pto to suppress plant immunity.

The fungal pathogen Ustilago maydis targets the maize corepressor TPL2 to modulate host transcription for tumorigenesis

This study identifies Tip6, an effector protein from Ustilago maydis, which interacts with ZmTPL2 to disrupt host transcriptional regulation and promote tumorigenesis.

Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

The paper investigates how early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination correlates with sustained anti-S antibody levels.

A transcriptional activator effector of Ustilago maydis regulates hyperplasia in maize during pathogen-induced tumor formation

This study identifies Sts2, an effector of Ustilago maydis, as a transcriptional activator that promotes tumor formation in maize by interacting with ZmNECAP1 and activating leaf developmental regulators.

Genetic and phosphoproteomic basis of LysM-mediated immune signaling in Marchantia polymorpha highlights conserved elements and new aspect of pattern-triggered immunity in land plants

This study identifies LysM receptor components and phosphoproteomic regulators of PTI in M. polymorpha, revealing conserved and novel elements of plant immune signaling.

Exploiting effector - host interactions using TurboID-based proximity labeling

The paper identifies host proteins interacting with the Ustilago maydis effector UmSee1 using TurboID-based proximity labeling, revealing three ubiquitin-proteasome pathway proteins involved in tumor formation during infection.

Contrasting and conserved roles of NPR pathways in diverged land plant lineages

This study compares NPR pathway functions across diverged land plants, finding conserved and divergent roles in stress responses and transcriptional regulation.

The cohesin subunit RAD21.2 functions as a recombination silencer of ribosomal DNA arrays

The paper identifies RAD21.2 as a repressor of meiotic recombination at rDNA regions in Arabidopsis, contributing to genome stability across generations.

miniTurbo-based interactomics of two plasma membrane-localized SNARE proteins in Marchantia polymorpha

The paper develops a miniTurbo-based interactomics method in Marchantia polymorpha to identify interactors of two SNARE proteins, showing it captures more specific candidates than co-immunoprecipitation.

Differential EDS1 requirement for cell death activities of plant TIR-domain proteins

The paper identifies four conserved TIR groups in land plants, two of which are EDS1-dependent and two are EDS1-independent in cell death activities.

The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines

The paper shows the Delta variant can escape NTD antibodies and gain infectivity when specific RBD mutations are present, suggesting the need for updated vaccines.

Agrobacterium-Mediated Transient Transformation of Marchantia Liverworts

This paper describes a method for Agrobacterium-mediated transient transformation in Marchantia liverworts and demonstrates its use for studying gene function and liverwort-bacteria interactions.

A versatile Tn7 transposon-based bioluminescence tagging tool for quantitative and spatial detection of bacteria in plants

This paper develops a Tn7 transposon-based bioluminescence tool for quantitative and spatial detection of bacteria in plants, validated across multiple species and immune responses.

Anti-CoVid19 plasmid DNA vaccine induces a potent immune response in rodents by Pyro-drive Jet Injector intradermal inoculation

This study evaluates a plasmid DNA vaccine against SARS-CoV-2 using a pyro-drive jet injector, showing strong immune response and protection in rodents.

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

The paper identifies two distinct modules, NRG1/EDS1/SAG101 and ADR1/EDS1/PAD4, required for TNL receptor immunity, showing effector recognition-dependent associations and functional requirements.

An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies

This study identifies an NTD site on SARS-CoV-2 spike protein that enhances infectivity when targeted by antibodies, and finds these antibodies are present in hospitalized patients and some uninfected donors.

The Phosphorylation Status of NPH3 Affects Photosensory Adaptation During the Phototropic Response

The study shows that phosphorylation of NPH3 affects its subcellular localization and the photosensory adaptation of phot1 signaling during phototropism.

The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN

This study identifies L-SIGN and DC-SIGN as receptors for the N-terminal domain of SARS-CoV-2 spike protein, showing their role in infection and the importance of anti-NTD antibodies.

Preclinical study of DNA vaccines targeting SARS-CoV-2

This study evaluates a DNA vaccine targeting SARS-CoV-2 Spike protein, showing enhanced humoral and cellular immune responses and neutralizing antibody activity.

SARS-CoV-2-induced humoral immunity through B cell epitope analysis and neutralizing activity in COVID-19 infected individuals in Japan

This study analyzes B cell epitopes and neutralizing activity in COVID-19 patients to identify potential vaccine targets.

CRK2 and C-terminal phosphorylation of NADPH oxidase RBOHD regulate ROS production in Arabidopsis

This study identifies CRK2 as a regulator of RBOHD-mediated ROS production in Arabidopsis, showing that CRK2 phosphorylates RBOHD's C-terminus to enhance defense against pathogens.

In planta bacterial multi-omics analysis illuminates regulatory principles underlying plant-pathogen interactions

The paper integrates transcriptome and proteome data from Pseudomonas syringae in Arabidopsis to reveal gene regulation patterns influenced by plant immunity.

SWITCH 1/DYAD is a novel WINGS APART-LIKE antagonist that maintains sister chromatid cohesion in meiosis

This study identifies SWITCH 1/DYAD as a novel WAPL antagonist in Arabidopsis meiosis that maintains sister chromatid cohesion, showing functional similarity to Sororin despite lacking sequence homology.