Author

M. Hashimoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 3 Plant Biology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

S.-Y. Chang· 3 shared T. Ching· 3 shared C.-H. Teng· 2 shared Y.-C. Toh· 2 shared A. L. Rajakrut· 1 shared A. Reinstaedler· 1 shared A. S. Ranganath· 1 shared B. Awuor· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBioengineering

S.-Y. Chang

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation

W. Kong, M. Hara, Y. Tokunaga, K. Okumura, Y. Hirano, J. Miao, Y. Takenoshita, M. Hashimoto, H. Sasaki, T. Fujimori, Y. Wakabayashi, T. Fukagawa

The paper identifies a regulatory loop between CENP-C and Aurora B kinase mediated by the Mis12 complex, essential for correcting kinetochore-microtubule attachment errors during mitosis.

bioRxiv · May 29, 2024Cell Biology

Organ-on-a-Chip Fabrication using Dynamic Photomask

T. Ching, S.-Y. Chang, Y.-C. Toh, M. Hashimoto

This paper introduces a dynamic photomask system for rapid organ-on-a-chip fabrication, enabling real-time design modifications and improved manufacturability.

bioRxiv · Nov 22, 2023Bioengineering

3D Bioprinting Using Poly(ethylene-glycol)-dimethacrylate (PEGDMA) Composite

S.-Y. Chang, J. Z. W. Lee, A. S. Ranganath, T. Ching, M. Hashimoto

This paper demonstrates the use of PEGDMA as a composite bioink to enhance mechanical properties in SLA bioprinting, supporting cell proliferation in vitro.

bioRxiv · Oct 19, 2023 · PreprintBioengineering

Quinoclamine inhibits Shiga toxin production in enterohemorrhagic Escherichia coli

O. Kar, H.-C. Feng, H. Hirano, C.-H. Teng, H. Osada, M. Hashimoto

This study identifies quinoclamine as an inhibitor of Shiga toxin 2 production in enterohemorrhagic Escherichia coli by preventing the SOS response.

bioRxiv · Sep 26, 2023 · PreprintMicrobiology

Biomimetic Vasculatures by 3D-Printed Porous Molds

T. Ching, j. vasudevan, S.-Y. Chang, H. Y. Tan, C. T. Lim, J. G. Fernandez, J. J. Ng, Y.-C. Toh, M. Hashimoto

This paper introduces a 3D-printed porous mold technique to create cell-laden, perfusable vascular models that mimic biological and anatomical features of blood vessels.

bioRxiv · Sep 27, 2021Bioengineering

Short 5'UTR enables optimal translation of plant virus tricistronic RNA via leaky scanning

Y. Fujimoto, T. Keima, M. Hashimoto, Y. Hagiwara-Komoda, N. Hosoe, S. Nishida, T. Nijo, K. Oshima, J. Verchot, S. Namba, Y. Yamaji

The paper investigates how a short 5'UTR enhances leaky scanning in plant virus tricistronic RNA, optimizing translation of multiple proteins and suggesting a conserved regulatory mechanism.

bioRxiv · May 14, 2021 · PreprintPlant Biology

A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota

P. Duran, A. Reinstaedler, A. L. Rajakrut, M. Hashimoto, R. Garrido-Oter, P. Schulze-Lefert, R. Panstruga

This study investigates how powdery mildew infection affects microbial communities in Arabidopsis thaliana, showing local and marginal systemic changes in foliar but not root-associated bacteria.

bioRxiv · Feb 26, 2021Plant Biology

Membrane-proximal external region is a superior target for mediating effector activity of HIV-1 specific chimeric antigen receptor modified T cells.

M. Kamata, E. Kranz, J. Chan, H. Wang, M. Hashimoto, T. Kanazawa

This paper develops a multicolor flow cytometry assay to compare anti-HIV-1 activity of different CAR constructs and identifies that CARs targeting the membrane-proximal external region show higher cytotoxicity than CD4{zeta} CAR.

bioRxiv · Mar 11, 2020 · PreprintMicrobiology

Pathogenicity of urinary tract infection Escherichia coli in Caenorhabditis elegans

M. Hashimoto, Y.-F. Ma, S.-T. Wang, C.-S. Chen, C.-H. Teng

This study establishes a C. elegans model to screen UPEC strains and identifies iron acquisition genes as key to pathogenicity.

bioRxiv · Nov 28, 2019Microbiology

Field evaluation of a quantitative, and rapid malaria diagnostic system using a fluorescent Blue-ray optical device

T. Mita, T. Yamamoto, M. Hashimoto, K. Nagatomi, T. Nogami, Y. Sofue, T. Hayashi, Y. Ido, S. Yatsushiro, K. Abe, K. Kajimoto, N. Tamari, B. Awuor, G. Sonye, J. Kongere, , M. Kataoka

The paper evaluates a quantitative malaria diagnostic system using a fluorescent Blue-ray optical device in Kenya, showing higher sensitivity and specificity than RDT.

bioRxiv · Jul 31, 2019 · PreprintPhysiology