K. M. Scherer

ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology for video-rate super-resolution imaging

ERnet quantifies ER topology dynamics using video-rate super-resolution imaging and semantic segmentation, enabling analysis of ER morphology changes in response to genetic or metabolic perturbations.

Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection

This study uses cryo-soft-X-ray tomography to image HSV-1 infected cells in near-native state, revealing morphological changes in organelles like mitochondria and cytoplasmic vesicles.

The SARS-CoV-2 nucleocapsid protein associates with the replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

This study tracks SARS-CoV-2 structural proteins' spatiotemporal dynamics during infection, revealing nucleocapsid's early association with ER membranes and lysosome involvement in viral egress.

Distinct domain requirements for EAP45 in HIV budding, late endosomal recruitment, and cytokinesis

This study identifies distinct domain requirements of EAP45 in HIV budding, late endosomal recruitment, and cytokinesis using fluorescent labeling and microscopy.

Combining sample expansion and light sheet microscopy for the volumetric imaging of virus-infected cells with optical super-resolution

This paper combines sample expansion with light sheet microscopy to achieve high-resolution 3D imaging of virus-infected cells, revealing new details of the infection cycle.

Spatiotemporal analysis of host cell modification during herpes simplex virus 1 replication

This study uses a recombinant reporter virus to analyze the spatiotemporal dynamics of host cell modifications during herpes simplex virus 1 replication.