Author

T. Kurz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:deep learning· 1 Organism:human· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Berger· 1 shared A. D. Baughn· 1 shared A. Easton· 1 shared A. Foltyn· 1 shared A. Latha· 1 shared A. M. Whiteley· 1 shared A.-L. Kiffe-Delf· 1 shared B. Burckhardt· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Berger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

α-Aminooxyacetic acid derivatives acting as pro-drugs against Mycobacterium tuberculosis

K. Vill, L. van Geelen, O. Michel, A.-L. Kiffe-Delf, A. Berger, D. Podlesainski, K. Stenzel, F. Kovacic, B. Lungerich, B. Burckhardt, T. A. :Crooks, M. D. Howe, L. Ostrer, Z. Jia, T. R. Ioerger, , R. Kalscheuer

This study identifies novel anti-TB pro-drugs based on α-aminooxyacetic acid that are effective against M. tuberculosis and show low cytotoxicity.

bioRxiv · Apr 4, 2024 · PreprintMicrobiology

Development of a Bipyrimidineamide based α-Helix Mimetic Lead Compound for efficient Targeting of MDM2 in Triple-Negative Breast Cancer

J. L. On, V. Woloschin, F. Gier, J.-W. Tu, S. Bhatia, T. Lenz, K. Stühler, D. Niederacher, H. Neubauer, T. Fehm, T. Kurz, K. Esser

This study develops a bipyrimidineamide-based α-helix mimetic compound, VWK603, which effectively targets MDM2 in TNBC cells with lower toxicity than Nutlin-3a.

bioRxiv · Mar 2, 2024 · PreprintCancer Biology

In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning

J. Kranich, N.-K. Chlis, L. Rausch, A. Latha, M. Schifferer, T. Kurz, A. Foltyn, M. Simons, F. J. Theis, T. Brocker

This paper introduces a method using fluorescent MFG-E8 and deep learning to identify apoptotic and EV-bound live cells in vivo, finding that most PS+ cells are live cells associated with EVs.

bioRxiv · Apr 14, 2020Cell Biology

Global proteomics of Ubqln2-based murine models of ALS

A. M. Whiteley, M. A. Prado, S. A. H. de Poot, J. A. Paulo, M. Ashton, S. Dominguez, M. Weber, H. Ngu, J. Szpyt, M. P. Jedrychowski, A. Easton, S. P. Gygi, T. Kurz, M. J. Monteiro, E. J. Brown, D. Finley

The paper identifies proteomic changes in Ubqln2 mutant mice and finds that TRIM32, PEG10, and CXX1B are linked to UBQLN2 function and degradation.

bioRxiv · Feb 22, 2020Cell Biology