Author

L. Cong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Bhutkar· 1 shared A. Li· 1 shared A. Regev· 1 shared C. G. Rappazzo· 1 shared C. J. Lim· 1 shared C. Q. Dang· 1 shared C. R. Detrick· 1 shared D. Canner· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bhutkar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Efficient and multiplexed somatic genome editing with Cas12a mice

J. D. Hebert, H. Xu, Y. J. Tang, P. A. Ruiz, C. R. Detrick, J. Wang, N. W. Hughes, O. Donosa, L. Andrejka, S. Karmakar, I. Aboiralor, R. Tang, J. Sage, L. Cong, D. Petrov, M. M. Winslow

This study develops transgenic Cas12a mice to enable efficient, multiplexed somatic genome editing for studying complex genetic interactions in vivo.

bioRxiv · Mar 7, 2024Cancer Biology

HIV-1 Vpu promotes phagocytosis of infected CD4+ T cells by macrophages through downregulation of CD47

L. Cong, S. M. Sugden, P. Leclair, C. J. Lim, T. N. Pham, E. A. Cohen

This study shows HIV-1 Vpu downregulates CD47 on infected CD4+ T cells, enhancing macrophage phagocytosis and enabling macrophage infection by T/F viruses.

bioRxiv · Mar 16, 2021Microbiology

Longitudinal single cell profiling of regulatory T cells identifies IL-33 as a driver of tumor immunosuppression

A. Li, R. H. Herbst, D. Canner, J. M. Schenkel, O. C. Smith, J. Y. Kim, M. Hillman, A. Bhutkar, M. S. Cuoco, C. G. Rappazzo, P. Rogers, C. Q. Dang, O. Rozenblatt-Rosen, L. Cong, M. Birnbaum, , T. Jacks

The paper identifies IL-33 as a driver of tumor immunosuppression by analyzing longitudinal single-cell RNA-Seq data of regulatory T cells in a mouse model of lung adenocarcinoma.

bioRxiv · Jan 6, 2019 · PreprintCancer Biology