A. Doostmohammadi

Emergent collective alignment gives competitive advantage to longer cells during range expansion

The paper shows longer bacterial cells gain a competitive advantage during range expansion through collective alignment, blocking shorter cells from resources.

Differential elasticity in lineage segregation of embryonic stem cells

The paper uses optical tweezers to measure mechanical elasticity differences in mouse embryonic stem cells during lineage segregation, showing elasticity drives segregation before differentiation commitment.

Mechanics of cell integration in vivo

The paper investigates how multiciliated cell precursors integrate into tissue by pulling on epithelial vertices, revealing mechanical interactions and the role of LSR in this process.

Mechanics of live cell elimination

This study uses a phase-field model to investigate the mechanical basis of cell extrusion in monolayers, linking extrusion events to stress relief and topological defects.

Activity pulses induce spontaneous flow reversals in viscoelastic environments

This study shows that activity pulses in active gels can induce spontaneous flow reversals in viscoelastic environments due to interactions between the active medium and the viscoelastic matrix.

Wrinkle force microscopy: a new machine learning based approach to predict cell mechanics from images

This paper introduces a machine learning method to predict cellular forces from microscope images by training on wrinkle patterns and traction force data.

Spatiotemporal model of cellular mechanotransduction via Rho and YAP

The paper develops a spatiotemporal model of YAP mechanotransduction involving Rho GTPases, predicting YAP nuclear-to-cytoplasmic ratios under varying mechanical stimuli.

Nature of active forces in tissues: how contractile cells can form extensile monolayers

The paper investigates how epithelial cell monolayers switch from extensile to contractile behavior as intercellular contacts weaken, revealing mechanotransductive responses and implications for cell sorting and tissue dynamics.

Filopodia rotate and coil by actively generating twist in their actin shaft

The paper shows filopodia rotate and coil by generating twist in their actin shaft through active dynamics, observed across various cell types.

Sustained oscillations of epithelial cell sheets

This study identifies a novel mode of collective oscillations in epithelial cell sheets under confinement, showing that oscillatory motion drives cellular movements and is regulated by confinement dimensions and force transmission.