T. Walter

The TissueTractor, a device for applying large strains to tissues and cells for simultaneous high-resolution live cell microscopy.

Long-read sequencing identifies aberrant fragmentation patterns linked to elevated cell-free DNA levels in cancer

The paper uses long-read sequencing to analyze cfDNA fragmentation patterns in cancer patients, identifying hypofragmentation and hyperfragmentation linked to elevated cfDNA levels.

Cell cycle-dependent mRNA localization in P-bodies

This study examines how mRNA localization to P-bodies changes during the cell cycle, revealing that mRNA dynamics in P-bodies are not solely linked to translation status but are regulated by RNA features and RBPs.

Self-supervised learning to predict intrahepatic cholangiocarcinoma transcriptomic classes on routine histology

This paper develops a self-supervised learning model to predict iCCA transcriptomic classes from histological images, achieving good to very good performance in multiple validation sets.

Streetlights affect moth orientation beyond flight-to-light behaviour

This study shows streetlights disrupt moth orientation beyond flight-to-light behavior, affecting movement patterns and potentially ecosystem services.

Automatic grading of cervical biopsies by combining full and self-supervision

This paper combines full and self-supervision to improve cervical biopsy grading, achieving high accuracy and interpretability.

Deep Learning identifies new morphological patterns of Homologous Recombination Deficiency in luminal breast cancers from whole slide images.

This study uses deep learning to identify new morphological patterns of HRD in luminal breast cancers from whole slide images, achieving high accuracy and enabling new hypotheses on phenotypic impacts.

Antibody evasion by the Brazilian P.1 strain of SARS-CoV-2

This study compares antibody resistance of SARS-CoV-2 variants P.1, B.1.351, and B.1.1.7, finding P.1 is less resistant to antibodies despite similar ACE2 binding mutations.

The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions

The paper identifies KIF1C as a motor transporting APC-dependent mRNAs to cell protrusions, showing its dual role in RNA transport and clustering.

TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields

TRex tracks multiple animals in real-time with markerless identification and estimates 2D posture and visual fields.

A localization screen reveals translation factories and widespread co-translational RNA targeting

The paper identifies translation factories and co-translational RNA targeting through a dual protein/mRNA localization screen in human cells.