Author

G. C. Paesen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:proteomics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

K. J. Doores· 2 shared T. A. Bowden· 2 shared A. Flaxman· 1 shared A. J. Mentzer· 1 shared A. J. Pollard· 1 shared A. Lundkvist· 1 shared A. Pauvolid-Correa· 1 shared A. Roe· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

K. J. Doores

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Author profile →

3 papers

Recent·Most cited

VelcroVax: a bolt-on vaccine platform technology improves antibody titres against a viral glycoprotein in mice

N. J. Stonehouse, N. J. Kingston, K. Grehan, J. S. Snowden, M. Hassall, J. Alzahrani, G. C. Paesen, L. Sherry, C. R. Hayward, A. Roe, S. Stephen, D. C. Tomlinson, A. Zeltina, K. J. Doores, N. A. Ranson, , D. J. Rowlands

VelcroVax is a vaccine platform that enhances antibody titres against a viral glycoprotein in mice by combining a modified VLP with a SUMO-tagged antigen.

bioRxiv · Apr 22, 2022 · PreprintImmunology

Antibody evasion by the Brazilian P.1 strain of SARS-CoV-2

W. - Dejnirattisai, D. - Zhou, P. - Supasa, C. - Liu, A. J. Mentzer, H. M. Ginn, Y. - Zhao, H. M. E. Duyvesteyn, A. Tuekprakhon, R. Nutalai, B. - Wang, G. C. Paesen, C. - Lopez-Camacho, J. - Slon-Campos, T. Walter, , Barne

This study compares antibody resistance of SARS-CoV-2 variants P.1, B.1.351, and B.1.1.7, finding P.1 is less resistant to antibodies despite similar ACE2 binding mutations.

bioRxiv · Mar 12, 2021Microbiology

Molecular rationale for hantavirus neutralization by a reservoir host-derived monoclonal antibody

I. Rissanen, R. Stass, S. A. Krumm, J. Seow, R. J. G. Hulswit, G. C. Paesen, J. Hepojoki, O. Vapalahti, A. Lundkvist, O. Reynard, V. Volchkov, K. J. Doores, J. T. Huiskonen, T. A. Bowden

This study investigates how a monoclonal antibody neutralizes hantaviruses by targeting the glycoprotein lattice, revealing structural insights into antibody binding and its impact on viral entry.

bioRxiv · Apr 17, 2020Microbiology