Ontogeny and function of the circadian clock in intestinal organoids
Andrew E. Rosselot, Miri Park, Mari Kim, Toru Matsuura, Gang Wu, Danilo E. F. L. Flôres, Krithika R. Subramanian, Suengwon Lee, Nambirajan Sundaram, Taylor R. Broda, Heather A. McCauley, Jennifer Hawkins, Kashish Chetal, Nathan Salomonis, Noah F. Shroyer, , Christian I. Hong
This study investigates circadian rhythms in human intestinal organoids, showing circadian phase-dependent necrotic cell death responses to TcdB and identifying anti-phasic gene expression between mouse and human enteroids.
The EMBO Journal · Oct 27, 2021Peer-reviewedMolecular Biology