Author

U. Laugks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Grünewald· 2 shared A. J. Koster· 1 shared A. Martinez-Sanchez· 1 shared A. W. M. de Jong· 1 shared B. Klupp· 1 shared C. Hagen· 1 shared D. A. Agard· 1 shared D. Vasishtan· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

K. Grünewald

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NECing goes: flexibility of the herpesvirus nuclear egress complex

V. Prazak, Y. Mironova, D. Vasishtan, C. Hagen, U. Laugks, Y. Jensen, S. Sanders, J. M. Heumann, J. B. Bosse, B. Klupp, T. C. Mettenleiter, M. Grange, K. Grünewald

This study examines the structure and flexibility of the herpesvirus nuclear egress complex (NEC) using electron cryo-tomography, revealing its hexameric lattice and role in capsid envelopment.

bioRxiv · Jul 7, 2023Microbiology

A molecular pore spans the double membrane of the coronavirus replication organelle

G. Wolff, R. W. A. L. Limpens, J. C. Zevenhoven-Dobbe, U. Laugks, S. Zheng, A. W. M. de Jong, R. I. Koning, D. A. Agard, K. Grünewald, A. J. Koster, E. J. Snijder, M. Barcena

The paper identifies a molecular pore in coronavirus replication organelles that facilitates RNA export to the cytosol, suggesting it as a potential drug target.

bioRxiv · Jun 25, 2020Microbiology

Template-free detection and classification of heterogeneous membrane-bound complexes in cryo-electron tomograms

A. Martinez-Sanchez, Z. Kochovski, U. Laugks, J. Meyer zum Alten Borgloh, S. Pfeffer, W. Baumeister, V. Lucic

The paper develops a template-free method to detect and classify membrane-bound complexes in cryo-ET data, revealing previously undetected ER translocon species and their structural and spatial characteristics.

bioRxiv · Jul 1, 2019Biophysics