Author

V. Greco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 8 Approach:experimental assay· 4 Assay:imaging· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 2 Approach:deep learning· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

C. Matte-Martone· 4 shared D. G. Gonzalez· 3 shared E. Lathrop· 3 shared K. Cockburn· 3 shared S. Ganesan· 3 shared J. L. Moore· 2 shared K. Annusver· 2 shared K. Kawaguchi· 2 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCell Biology

C. Matte-Martone

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Author profile →

8 papers

Recent·Most cited

Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermis in vivo

A. Hemalatha, Z. Li, K. Tai, D. G. Gonzalez, E. Lathrop, D. Gil, C. Matte-Martone, S. Ganesan, S. Yun, L. E. Gonzalez, M. C. Skala, R. J. Perry, V. Greco

The paper investigates metabolic adaptations in winner and loser oncogenic mutant stem cells in skin epidermis, revealing distinct metabolic strategies that drive cell competition outcomes.

bioRxiv · Nov 21, 2022 · PreprintCancer Biology

Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation

T. Xin, S. Gallini, D. Gonzalez, L. E. Gonzalez, S. Regot, V. Greco

This study shows that oncogenic KrasG12D causes tissue deformation by converting pulsatile ERK signals into sustained activation, disrupting stem cell coordination in hair follicles.

bioRxiv · Sep 14, 2022Cancer Biology

Injury suppresses Ras cell competitive advantage through enhanced wild-type cell proliferation

S. Gallini, N.-T. Rahman, K. Annusver, D. G. Gonzalez, S. Yun, C. Matte-Martone, T. Xin, E. Lathrop, K. C. S. C. Suozzi, M. Kasper, V. Greco

Injury-repair selectively induces wild-type cell proliferation to suppress oncogenic growth in Ras-mosaic skin epithelium.

bioRxiv · Jan 5, 2022Cell Biology

G2 stem cells orchestrate time-directed, long-range coordination of calcium signaling during skin epidermal regeneration

J. L. Moore, F. Gao, C. Matte-Martone, S. Du, E. Lathrop, S. Ganesan, L. Shao, D. Bhaskar, A. Cox, C. E. Hendry, B. A. Rieck, S. Krishnaswamy, V. Greco

The paper uses a new machine learning tool to analyze calcium signaling dynamics in epidermal stem cells during regeneration, revealing that G2 stem cells coordinate long-range signaling through gap junctions.

bioRxiv · Oct 12, 2021Cell Biology

Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks

T. Yamamoto, K. Cockburn, V. Greco, K. Kawaguchi

The paper uses graph neural networks to infer cell coordination rules from live tissue data, revealing region-specific coordination patterns in mammalian epidermis.

bioRxiv · Jun 23, 2021Cell Biology

Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis

S. Park, C. Matte-Martone, D. G. Gonzalez, E. A. Lathrop, D. P. May, C. M. Pineda, J. L. Moore, J. D. Boucher, E. D. Marsh, A. Schmitter, K. Cockburn, Y. Bellaiche, V. Greco

The paper tracks immune cells in live mice to show they maintain a tiling pattern with epithelial cells during homeostasis, regulated by epithelial density and Rac1.

bioRxiv · Jan 8, 2021Cell Biology

Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer.

K. Cockburn, K. Annusver, S. Ganesan, K. R. Mesa, K. Kawaguchi, M. Kasper, V. Greco

The paper shows that epidermal stem cells undergo gradual differentiation without exiting the cell cycle, generating heterogeneity in the stem cell layer.

bioRxiv · Jan 7, 2021Cell Biology

3D super-resolution deep-tissue imaging in living mice

M. G. M. Velasco, M. Zhang, J. Antonello, P. Yuan, E. S. Allgeyer, D. May, O. M'Saad, P. Kidd, A. E. S. Barentine, V. Greco, J. Grutzendler, M. J. Booth, J. Bewersdorf

This paper develops a STED system for 3D super-resolution imaging in living mice, achieving depths of 76 micrometers in brain tissue.

bioRxiv · Oct 2, 2019Biophysics