Author

K. R. Mesa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Assay:flow cytometry· 1

Frequent Co-Authors

D. R. Littman· 3 shared A. Dolynuk· 1 shared A. Grayson· 1 shared A. T. Satpathy· 1 shared B. D. Keister· 1 shared C. A. Lareau· 1 shared C. Ng· 1 shared H. Nguyen· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

D. R. Littman

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Author profile →

5 papers

Recent·Most cited

Niche-specific macrophage loss promotes skin capillary aging

K. R. Mesa, K. A. O'Connor, C. Ng, S. Salvatore, A. Dolynuk, M. Rivera Lomeli, D. R. Littman

This study shows that loss of capillary-associated macrophages with age impairs vascular repair and perfusion, revealing limitations in macrophage homeostatic renewal in skin capillaries.

bioRxiv · Aug 25, 2023 · PreprintImmunology

Microbiota-instructed regulatory T cell differentiation is mediated by a distinct RORγt+ antigen presenting cell subset

R. Kedmi, T. Najar, K. R. Mesa, A. Grayson, L. Kroehling, Y. Hao, S. Hao, M. Pokrovskii, M. Xu, J. Talbot, J. Wang, J. Germino, C. A. Lareau, A. T. Satpathy, M. S. Anderson, , D. R. Littman

This study identifies a distinct RORγt+ antigen presenting cell subset that mediates microbiota-driven regulatory T cell differentiation, revealing a mechanism for maintaining immune tolerance.

bioRxiv · Nov 19, 2021 · PreprintImmunology

Arkadia-SKI/SnoN signaling cascade differentially regulates TGF-β-induced iTreg and Th17 cell differentiation

H. Xu, L. Wu, H. Nguyen, K. R. Mesa, V. Raghavan, V. Episkopou, D. R. Littman

This study identifies Arkadia-SKI/SnoN signaling as a regulator of TGF-β-induced iTreg differentiation, distinct from Th17 cell differentiation.

bioRxiv · Feb 23, 2021Immunology

Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer.

K. Cockburn, K. Annusver, S. Ganesan, K. R. Mesa, K. Kawaguchi, M. Kasper, V. Greco

The paper shows that epidermal stem cells undergo gradual differentiation without exiting the cell cycle, generating heterogeneity in the stem cell layer.

bioRxiv · Jan 7, 2021Cell Biology

Apoptotic Cells May Drive Cell Death in Hair Follicles During their Regression Cycle

K. B. Blagoev, B. D. Keister, K. R. Mesa

The paper investigates apoptosis propagation in hair follicles during regression, finding that apoptotic cells induce neighboring cell death and that stem cells may send a pro-survival signal to slow apoptosis.

bioRxiv · Nov 16, 2020Cell Biology