J.-E. Park

Rapid and label-free exosome analysis by surface-enhanced Raman spectroscopy using silver nanoparticle substrate based on selective laser ablation and melting of silver nanowire

This paper presents a rapid, label-free method for detecting breast cancer-derived exosomes using SERS with a silver nanoparticle substrate fabricated via laser ablation and melting.

Altitude-dependent agro-ecologies impact the microbiome diversity of scavenging indigenous chicken in Ethiopia

The study examines how altitude-dependent agro-ecologies affect the microbiome diversity of scavenging indigenous chickens in Ethiopia, identifying environmental factors influencing microbial composition.

Diffsig: Associating Risk Factors With Mutational Signatures

Diffsig estimates associations between risk factors and mutational signatures using a Bayesian model, confirming known cancer mechanisms in breast cancer data.

Mapping the developing human immune system across organs

This study maps the developing human immune system across organs using single-cell RNA sequencing, antigen-receptor sequencing, and spatial transcriptomics, revealing cross-gestation and cross-organ variability and identifying prenatal B1 cells and unconventional T cell origins.

Clathrin-mediated Endocytosis Facilitates Internalization of Magnaporthe oryzae Effectors into Rice Cells

This study shows that Magnaporthe oryzae uses clathrin-mediated endocytosis to internalize effector proteins into rice cells.

Poised cell circuits in human skin are activated in disease

The paper creates a single-cell atlas of human skin, showing how cell circuits change in inflammatory diseases like atopic dermatitis and psoriasis.

Reconstitution of Alveolar Regeneration via novel DATPs by Inflammatory Niches

The paper identifies DATPs as a novel progenitor population in alveolar regeneration and shows how IL-1β-mediated inflammation impairs their differentiation into mature AT1 cells.

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.

The paper uses single-cell RNA sequencing to analyze immature human thymocytes and identifies thymus seeding precursors and T-lineage developmental pathways.

A cell atlas of human thymic development defines T cell repertoire formation

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.