Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level
Birthe Dorgau, Joseph Collin, Agata L. Rozanska, Veronika Boczonadi, Marina Moya Molina, Adrienne A. Unsworth, Rafiqul Hussain, Jonathan M Coxhead, Tamil Dhanaseelan, Lyle Armstrong, Rachel A. Queen, Majlinda Lako
This study presents the first single-cell spatio-temporal transcriptome of human retinal organoid development using single-cell RNA-Seq and spatial transcriptomics, revealing key developmental events and chromatin accessibility patterns.
iScience · Mar 4, 2024Peer-reviewedDevelopmental Biology