Author

Vivian Morris

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

George Q. DaleyiD· 3 shared Dahai WangiD· 2 shared Edroaldo Lummertz da RochaiD· 2 shared R. Grant RoweiD· 2 shared Trista E. NorthiD· 2 shared Allison Tompkins· 1 shared Anton AfanassieviD· 1 shared Anup VaidyaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersDevelopmental Biology

George Q. DaleyORCID

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3 papers

Recent·Most cited

Heterochromatin fidelity is a therapeutic vulnerability in lymphoma and other human cancers

Mohamad Ali Toufic Najia, Deepak Kumar Jha, Cheng Zhang, Benoît Laurent, Caroline Kubaczka, Arianna Markel, Christopher Li, Vivian Morris, Allison Tompkins, Luca T. Hensch, Yue Qin, Bjoern Chapuy, Yu-Chung Huang, Michael Morse, Matthew R. Marunde, , George Q. Daley

The paper identifies KDM4 demethylase inhibition as a therapeutic strategy for lymphoma and other cancers by rewiring heterochromatin and inducing DNA damage.

bioRxiv · Jan 31, 2025 · PreprintGenomics

Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-PRC1 axis

Dahai Wang, Mayuri Tanaka-Yano, Eleanor Meader, Melissa A. Kinney, Vivian Morris, Edroaldo Lummertz da Rocha, Nan Liu, Stuart H. Orkin, Trista E. North, George Q. Daley, R. Grant Rowe

The paper identifies a Lin28b-let-7-PRC1 axis that regulates hematopoietic maturation across development, with Cbx2 playing a key role in controlling developmental timing of hematopoietic transcription factors.

bioRxiv · Jan 5, 2022 · PreprintDevelopmental Biology

Hematopoiesis at single cell resolution spanning human development and maturation

Hojun Li, Jideofor Ezike, Anton Afanassiev, Laura Greenstreet, Stephen X. Zhang, Jennifer Whangbo, Vincent L. Butty, Enrico Moiso, Guinevere G. Connelly, Vivian Morris, Dahai Wang, George Q. Daley, Salil Garg, Stella T. Chou, Aviv Regev, , R. Grant Rowe

The paper uses single cell RNA-seq to study human hematopoietic stem and progenitor cells (HSPCs) across development and aging, revealing age-related transcriptional changes and differentiation trajectories.

bioRxiv · Aug 25, 2021 · PreprintDevelopmental Biology