Author

W. Wurst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Organism:plant (other)· 1

Frequent Co-Authors

E. Wolf· 2 shared A. Baehr· 1 shared A. Baron· 1 shared A. Konnerth· 1 shared A. Moretti· 1 shared A. Strohmeyer· 1 shared A. Worthmann· 1 shared B. Rathkolb· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPhysiology

E. Wolf

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ

G. S. Hönes, D. Geist, C. Wenzek, P. T. Pfluger, T. D. Müller, O. V. Amarie, L. Becker, N. Dragano, L. Garrett, S. M. Hölter, B. Rathkolb, J. Rozman, N. Spielmann, I. Treise, E. Wolf, , L. C. Moeller

This study compares TRα and TRβ knockout mice with DNA-binding-deficient mutants to show noncanonical TR signaling contributes to physiological functions beyond canonical genomic pathways.

bioRxiv · Nov 26, 2023Physiology

Gene Therapy for Cardiomyopathy associated with Duchenne Muscular Dystrophy in a Pig Model

A. Baehr, P. Hoppmann, T. Bozoglu, M. Stirm, I. Luksch, T. Ziegler, N. Hornaschewitz, S. Shresta, B. Shashikadze, J. B. Stöckl, N. Raad, H. Blum, S. Krebs, T. Fröhlich, C. Baumgartner, , C. Kupatt

This study shows that AAV1.SERCA2a gene therapy improves heart function and reduces arrhythmia in a pig model of Duchenne muscular dystrophy.

bioRxiv · Oct 2, 2023 · PreprintPhysiology

Susceptibility to diet induced obesity at thermoneutral conditions is independent of UCP1

S. Dieckmann, A. Strohmeyer, M. Willershaeuser, S. Maurer, W. Wurst, S. Marschall, M. Hrabe de Angelis, R. Kuehn, A. Worthmann, M. M. Fuh, J. Heeren, N. Koehler, J. Pauling, M. Klingenspor

This study shows that UCP1 deletion does not affect diet-induced obesity at thermoneutrality and introduces a novel UCP1-KO mouse model.

bioRxiv · Jun 30, 2021Physiology

PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis

E. Danileviciute, N. Zeng, C. Capelle, N. Paczia, M. A. Gillespie, H. Kurniawan, D. Coowar, D. Vogt-Weisenhorn, G. Gomez-Giro, M. Grusdat, A. Baron, C. Guerin, D. G. Franchina, C. Leonard, O. Domingues, , F. Q. He

This study shows PARK7/DJ-1 enhances PDH activity in Tregs by inhibiting PDHA phosphorylation, maintaining Treg homeostasis and reducing EAE severity.

bioRxiv · Dec 20, 2019Biochemistry

Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo

C. Fecher, L. Trovo, S. A. Müller, N. Snaidero, J. Wettmarshausen, S. Heink, O. Ortiz, I. Wagner, R. Kühn, J. Hartmann, R. M. Karl, A. Konnerth, T. Korn, W. Wurst, D. Merkler, , T. Misgeld

The paper profiles mitochondrial proteomes in specific neural cell types to reveal functional and molecular diversity across cell types in mice and humans.

bioRxiv · Aug 29, 2018Cell Biology