Hemispheric Asymmetry of Tau Pathology is Related to Asymmetric Amyloid Deposition in Alzheimer's Disease
Toomas Erik Anijärv, Rik Ossenkoppele, Ruben A Smith, Alexa Pichet Binette, Lyduine Eisa Collij, Hamid Behjat, Jonathan Ö. Rittmo, Linda Karlsson, Khazar Ahmadi, Olof T. Strandberg, the Alzheimer’s Disease Neuroimaging Initiative, Michael Walter Weiner, Paul S. S Aisen, Ronald Carl Petersen, Clifford R. Jack, , Oskar Hansson
The paper investigates whether hemispheric asymmetry in tau pathology in Alzheimer's disease is linked to reduced inter-hemispheric connectivity or asymmetric amyloid-beta distribution, finding a strong association with amyloid-beta laterality.
Nature Communications · Sep 5, 2025Peer-reviewedNeuroscience