Author

X. X. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:imaging· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Z. Rosenberg· 4 shared M. Levi· 4 shared B. A. Jones· 3 shared K. Myakala· 3 shared J. B. Kopp· 2 shared P. Daneshpajouhnejad· 2 shared A. E. Libby· 1 shared A. M. De Marzo· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersPathology

A. Z. Rosenberg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

X. X. Wang, K. Myakala, A. E. Libby, S. Ranjit, S. Takahashi, B. A. Jones, K. Bhasin, Y. Qi, K. Krausz, P. Zerfas, J. Panov, t. J. velenosi, d. P. patel, P. Daneshpajouhnejad, A. Titievsky, , M. Levi

This study shows that ERR agonism improves mitochondrial function and reduces inflammation in aging kidneys, while STING inhibition also reduces inflammation and increases mitochondrial gene expression.

The American Journal of Pathology · Dec 1, 2023Peer-reviewedPathology

Farnesoid X receptor agonism prevents neutrophil extracellular traps via reduced sphingosine-1-phosphate in chronic kidney disease

B. A. Jones, K. Myakala, M. Guha, S. Davidson, S. Adapa, I. Lopez Santiago, I. Schaffer, Y. Yue, J. Allegood, L. A. Cowart, X. X. Wang, A. Z. Rosenberg, M. Levi

This study shows FXR agonism reduces kidney NETosis in male mice by inhibiting S1P signaling, but not in females.

bioRxiv · Mar 1, 2023Pharmacology & Toxicology

PodoCount: A robust, fully automated whole-slide podocyte quantification tool

B. A. Santo, D. Govind, P. Daneshpajouhnejad, X. Yang, X. X. Wang, K. Myakala, B. A. Jones, M. Levi, J. B. Kopp, L. J. Niedernhofer, D. Manthey, K. C. Moon, S. S. Han, A. Z. Rosenberg, P. Sarder

PodoCount quantifies podocytes in kidney tissues with high accuracy, showing strong correlation with disease diagnosis and clinical outcomes in both murine models and human diabetic nephropathy.

bioRxiv · Apr 27, 2021Pathology

An in situ atlas of mitochondrial DNA in mammalian tissues reveals high content in stem/progenitor cells

J. Chen, Q. Zheng, L. B. Peiffer, J. L. Hicks, M. C. Haffner, A. Z. Rosenberg, M. Levi, X. X. Wang, B. Ozbek, S. Yegnasubramanian, A. M. De Marzo

The paper creates an in situ atlas of mitochondrial DNA in mammalian tissues, revealing higher mtDNA content in stem/progenitor cells and age-related decreases in renal tubules.

bioRxiv · Dec 19, 2019Pathology

Natural Amelioration of Mn-induced Chlorosis Facilitated by Mn Down-regulation, Ammonium and Rainwater in Sugarcane Seedlings

X. F. Li, G. Z. Ling, X. X. Wang, S. Yang, X. L. Tang, S. J. Jia, M. M. Chang

This study shows that Mn-induced chlorosis in sugarcane seedlings can naturally resolve through Mn downregulation, ammonium, and rainwater, leading to greening.

bioRxiv · Apr 24, 2019 · PreprintPlant Biology