Y. Kubota

Nuclear membrane protein Bqt4 maintains nuclear envelope integrity by recruiting phosphatidic acid

This study identifies Bqt4 as an inner nuclear membrane protein that recruits phosphatidic acid to maintain nuclear envelope integrity in fission yeast.

Mapping Natural Product Biosynthetic Hotspots: Prioritizing Conservation for Medicinal Resources

This study maps natural product biosynthetic hotspots by analyzing enzyme distribution in woody angiosperms, revealing correlations with biodiversity hotspots and suggesting targeted conservation strategies.

Unique and shared functions of the Rad9-Hus1-Rad1 and Mre11-Rad50-Nbs1 complexes in ATR checkpoint activation and long-range DNA end resection in Xenopus egg extracts

This study investigates the roles of MRN and 9-1-1 complexes in ATR checkpoint activation and DNA end resection using Xenopus egg extracts.

Occurrence-based diversity estimation reveals macroecological and conservation knowledge gaps for global woody plants

The paper estimates global woody plant diversity using occurrence records, revealing knowledge gaps and conservation priorities in underexplored regions.

Emergence of rhythmic chunking in complex stepping of mice

This study identifies rhythmic chunking in mice stepping, showing consistent cycle and phase patterns within chunks and linking licking behavior to these rhythms.

Germline-specific role for unconventional components of the γ-tubulin complex in Caenorhabditis elegans

This study identifies GTAP-1 and GTAP-2 as unconventional γ-tubulin complex components in C. elegans that target the complex to centrosomes and germ-cell membranes, affecting microtubule organization.

Increased mitochondrial Ca2+ contributes to health decline with age and Duchene muscular dystrophy in C. elegans.

This study shows that reducing mitochondrial calcium influx in C. elegans improves age-related and muscular dystrophy muscle decline by mitigating mitochondrial dysfunction.

Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2

This study identifies PLXDC2 as a marker for isolating hematopoietic stem cells (HSCs) in both mouse and human, showing its utility in transplantation and xenograft models.

Change in the bladder function of rats with focal cerebral infarction induced by photochemically-induced thrombosis

This study establishes a rat model of urinary frequency after focal cerebral infarction using photothrombosis, showing altered micturition intervals and no fatal outcomes.

Area-based conservation planning in Japan: protected area network effectiveness to the post-2020 Global Biodiversity Framework

This study evaluates the effectiveness of Japan's protected area network under the post-2020 Global Biodiversity Framework using spatial prioritization and land-use analysis.

Quantitative modeling of regular retinal microglia distribution

The paper quantitatively analyzes microglia distribution regularity, formulates a mathematical model, and identifies direct cell-cell contact as the key factor in generating regular spacing.

A geometric approach to scaling individual distributions to macroecological patterns

The paper develops a geometric framework to derive macroecological patterns from individual distribution data, recovering known patterns and providing new insights into their relationships.