M. Matsumoto

Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms

This study develops a live-attenuated SARS-CoV-2 vaccine candidate, BK2102, which induces long-term immunity and is safe in animal models.

TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

Acidovorax temperans polarizes T17 cells and skews neutrophil maturation to promote lung adenocarcinoma development

This study shows Acidovorax temperans promotes lung adenocarcinoma by altering neutrophil maturation and T17 cell polarization, enhancing tumor-associated inflammation.

Novel Antibody Interfaces Revealed Through Structural Mining

This study identifies novel antibody interfaces through structural analysis, revealing recurrent motifs and enabling their functional validation and optimization.

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

This study identifies EROS as a chaperone essential for gp91phox maturation and P2X7 receptor function, revealing its role in immune responses and infection resistance.

Change in the bladder function of rats with focal cerebral infarction induced by photochemically-induced thrombosis

This study establishes a rat model of urinary frequency after focal cerebral infarction using photothrombosis, showing altered micturition intervals and no fatal outcomes.

Most of Tobacco Male Meiocytes Are Involved in Intercellular Nuclear Migration at the First Meiotic Prophase

The paper uses serial block-face scanning electron microscopy to show that intercellular nuclear migration occurs in nearly all tobacco meiocytes during the first meiotic prophase.

Ferroptosis is programmed by the coordinated regulation of glutathione and iron metabolism by BACH1

This study identifies BACH1 as a regulator of ferroptosis by modulating glutathione and iron metabolism, showing its role in myocardial infarction resistance.