Author

Yuqi Bian

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Alicia González DíaziD· 3 shared Michele VendruscoloiD· 3 shared Andrea Possenti· 2 shared Benedetta ManniniiD· 2 shared Christine Maria LimiD· 2 shared Gustavo Antonio Urrutia· 2 shared Alex A. ZhavoronkoviD· 1 shared Danilo LicastroiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBioinformatics

Alicia González DíazORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Organization of the Proteostasis Network of Membraneless Organelles

Christine Maria Lim, Yuqi Bian, Alicia González Díaz, Frank W. Pun, Alex A. Zhavoronkov, Richard I. Morimoto, Michele Vendruscolo

The paper maps the proteostasis network of membraneless organelles, revealing the role of anabolic components and molecular chaperones in regulating protein conformations.

Advanced Science · Jun 11, 2025Peer-reviewedBioinformatics

A human neuronal model of sporadic Alzheimer's disease induced by FBXO2 downregulation shows A β aggregation, tau hyperphosphorylation and functional network impairment

Alicia González Díaz, Andrea Possenti, Gustavo Antonio Urrutia, Yuqi Bian, Shekhar Kedia, Dorothea Böken, Christine Maria Lim, Danilo Licastro, Benedetta Mannini, David Klenerman, Michele Vendruscolo

This study shows that downregulating FBXO2 in human iPSC-derived neurons leads to Alzheimer's disease-like features including Aβ aggregation and tau hyperphosphorylation.

bioRxiv · Sep 1, 2024 · PreprintNeuroscience

In situ generation of Aβ42 oligomers via secondary nucleation triggers neurite degeneration and synaptic dysfunction in human iPSC-derived glutamatergic neurons

Alicia González Díaz, Eleonora Sarracco, Andrea Possenti, Isaac Kitchen-Smith, Sean Chia, Joseph Menzies, Gabriel Stephenson, Rodrigo Cataldi, Kim Yahya, Yuqi Bian, Gustavo Antonio Urrutia, Sara Snogerup Linse, Benedetta Mannini, Michele Vendruscolo

This study generates Aβ42 oligomers in human iPSC-derived neurons to model Alzheimer's disease and assess inhibitor effects.

bioRxiv · Aug 30, 2024 · PreprintCell Biology