Z. Qian

Variability in donor lung culture and relative humidity impact the stability of 2009 pandemic H1N1 influenza virus on nonporous surfaces

This study examines how donor lung culture variability and relative humidity affect the stability of H1N1pdm09 virus on nonporous surfaces, finding that donor differences impact persistence more than surface material.

A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum Targeting

The paper identifies a host metabolic pathway essential for coronavirus replication and shows that inhibiting it with Propranolol has broad antiviral effects.

Genomic underpinnings of convergent adaptation to high altitudes for alpine plants

This study identifies genomic signatures of convergent adaptation to high altitudes in alpine plants by analyzing reference genomes and gene expression profiles.

Optimization and deoptimization of codons in SARS-CoV-2 and the implications for vaccine development

This study analyzes codon usage changes in SARS-CoV-2 over time, finds that deoptimization may reduce protein expression, and designs codon-optimized mRNA vaccine candidates for Omicron variants.

A Bispecific Antibody Targeting RBD and S2 Potently Neutralizes SARS-CoV-2 Omicron and Other Variants of Concern

This paper develops a bispecific antibody that targets both RBD and S2 of SARS-CoV-2, showing improved neutralization against Omicron and other variants compared to its parental monoclonal antibodies.

The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2

This study identifies RaACE2 as a functional receptor for SARS-CoV-2 and RaTG13, and evaluates ACE2s from 16 species for their ability to mediate virus entry.

Sensing Traction Force on Matrix Induces Cell-Cell Distant Mechanical Communications for Self-assembly

This study shows cells can sense long-range biomechanical forces through the matrix to initiate distant mechanical communication, enabling coordinated self-assembly.

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

The paper identifies gene expression differences between human and non-human primate brains at single-cell resolution, revealing rapid evolution in specific cell types.

Neural Multi-Scale Self-Supervised Registration for Echocardiogram Dense Tracking

This paper introduces NMSR, a neural multi-scale self-supervised registration method for automated myocardial and cardiac blood flow dense tracking in echocardiograms, showing improved accuracy over existing methods.

Resting heart rate and psychopathy: Findings from the Add Health Survey

This study examines the relationship between resting heart rate and psychopathic traits using a large national sample, finding no significant association after controlling for age, sex, and race.