Z. Ye

This study develops a far-red probe and microfluidic platform to image live erythrocyte membranes at the single-molecule level, enabling high-throughput super-resolution and tracking.

This study investigates how MLL3/MLL4 histone methyltransferase activity influences enhancer-promoter contacts and gene activation during mouse embryonic stem cell differentiation.

The paper shows that exchanging viral backbone genes can increase neuraminidase content in influenza virions, leading to better NA antibody responses in mice.

This study identifies 129 loci associated with 27 yield-related traits in tomato, explaining 8.8% of phenotypic variance, and highlights a candidate gene involved in leaf stomata formation and drought resistance.

This study identifies an epigenetic vulnerability in PI3K/AKT inhibitor-resistant cancers, showing that targeting bromodomain or HDAC inhibitors can overcome resistance by modulating histone acetylation at growth factor/receptor gene loci.

This study improves NADPH flux and xylitol production in engineered E. coli by dynamically controlling regulatory metabolites and metabolic pathways.

This study uses dynamic metabolic control to enhance stationary phase biosynthesis in E. coli by targeting citrate synthase and glucose-6-phosphate dehydrogenase, leading to increased acetyl-CoA production and citramalic acid titers.

This study identifies ZNF416 as a key transcriptional regulator that mediates fibroblast responses to matrix stiffness through chromatin accessibility and gene expression changes.

The paper shows that monounsaturated fatty acids (MUFA) are essential for B cell function and humoral immunity, with SCD-mediated MUFA production supporting early B cell development and germinal center formation.

This paper shows that HCFC1 and HCFC1R1 deficiencies block HSV-1 infection by inhibiting nuclear translocation of HCFC1 and VP16, offering potential new therapeutic targets.

This study reveals the recombinational landscape in Daphnia pulex using linkage disequilibrium analysis, showing uniform recombination and rejecting existing population-genetic models.

This study uses genomic analyses to show that metabolism-related genes drive local adaptation in Daphnia pulex populations.

This study shows that IL-1β disrupts β-cell circadian clocks by impairing Bmal1 expression and alters its DNA-binding patterns, linking circadian disruption to β-cell failure in diabetes.

The paper shows acidosis activates MondoA by increasing mitochondrial ATP production, which leads to G6P synthesis and nuclear MondoA translocation.

This study shows Ras suppresses TXNIP translation by slowing ribosome translocation, despite increasing overall protein synthesis.

This study identifies EZH2 as a p53 mRNA-binding protein that enhances translation of gain-of-function p53 mutants, promoting cancer growth and metastasis, and shows that inhibiting EZH2 causes synthetic lethality in these cells.