Shruti Khare

The paper integrates multiple datasets to create a comprehensive human liver cell atlas, identifying new cell types and associations with demographic factors.

This study integrates chromatin accessibility and transcriptomics data from ovarian tumor-infiltrating adaptive NK cells to identify key transcription factors and their regulatory networks.

This study shows that antigen-specific memory NK cells can be generated in ovarian cancer, enhancing their cytotoxicity and tumor reactivity through NKG2C/A-HLA-E/ABC interactions and CXCR2-mediated migration.

The paper shows that ccdA antitoxin in E. coli is highly sensitive to mutations, including synonymous ones, due to codon usage and operonic context effects on translation efficiency.

The paper shows that synonymous mutations can cause loss of function by altering RNA structure and gene expression ratios, validated in multiple operons.