Nicolas Bidère

This study identifies CK1 as a regulator of lysosomal fitness and ferroptotic sensitivity in glioblastoma stem-like cells through molecular glue degraders.

This study identifies CK1 as a bimodal regulator of the cGAS-STING pathway, showing it both promotes DNA sensing and facilitates signaling termination, with therapeutic implications for cancer.

This study shows that linear ubiquitination, mediated by LUBAC, is essential for the execution phase of NLRP3-mediated pyroptosis, independent of priming.

The paper identifies DNA-PKcs as a regulator of cyclic dinucleotide signaling, showing it interacts with CDN and modulates STING activation and antiviral responses.