Author
Centre National de la Recherche ScientifiqueORCID 0000-0003-0749-9871Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jane Jardine, Margaux Le Guyon, Kilian Trillet…·Nicolas Bidère
This study identifies CK1 as a regulator of lysosomal fitness and ferroptotic sensitivity in glioblastoma stem-like cells through molecular glue degraders.
Jane Jardine, Marine Tarrillon, Gwennan André‐Grégoire…·Nicolas Bidère
This study identifies CK1 as a bimodal regulator of the cGAS-STING pathway, showing it both promotes DNA sensing and facilitates signaling termination, with therapeutic implications for cancer.
Tiphaine Douanne, Rosalie Moreau, Valeria Trapani…·Nicolas Bidère
This study shows that linear ubiquitination, mediated by LUBAC, is essential for the execution phase of NLRP3-mediated pyroptosis, independent of priming.
Isabelle K. Vila, Yasmine Messaoud-Nacer, Clara Taffoni…·Nadine Laguette
The paper identifies DNA-PKcs as a regulator of cyclic dinucleotide signaling, showing it interacts with CDN and modulates STING activation and antiviral responses.